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Life Science Update 2026 research-hero-image Life Science Update 2026 research-image mobile

Life Sciences Update

Capital returns in force, even as real estate works toward balance 

Cushman & Wakefield’s latest life sciences market report External Link breaks down the major trends shaping the industry, from resurgent capital markets and accelerated dealmaking to how real estate is performing across established hubs and fast-growing emerging markets. 

Pharma and biotech companies significantly ramped up dealmaking in the first half of 2026, with M&A volume nearly tripling year-over-year (YOY) to $97.2 billion, and partnership activity climbing 18% to $108 billion. After several muted years, the IPO market roared back with $6.8 billion in offerings, while funding for AI-driven drug discovery surged 49% to $7.8 billion, underscoring investors' growing conviction in the sector’s next wave of innovation. 

Real estate fundamentals are beginning to reflect this improvement, even as the market continues working through excess supply. Global lab and cGMP rents softened modestly, down 0.5% YOY, and vacancy climbed to 24.2% as newly delivered space came online. However, the pace of vacancy growth is decelerating, and construction pipelines have contracted sharply across most major markets—signaling the sector may be approaching peak vacancy. 

Capital markets told a similarly encouraging story. Global R&D investment sales reached $13.2 billion, up 2% YOY, while venture capital (VC) funding jumped 30% to $29.9 billion, its strongest first-half showing since 2022. The U.S. saw even sharper gains, with VC funding up 37% and IPO volume up 232% YOY. Europe's recovery gained traction as well, aided by improving debt markets, growing M&A activity, and expanding public sector innovation funding, while the Chinese mainland continued advancing up the global value chain through record licensing activity. 

Looking ahead, the life sciences real estate sector still faces headwinds—elevated vacancy, cautious tenant demand in some markets, and a more selective funding environment for early-stage companies. But with capital markets rebounding, clinical trial activity expanding and construction pipelines thinning, the industry is well positioned for a constructive second half of 2026 and beyond. 

GLOBAL MARKETS

Select each city on the map below to view an in-depth life sciences market summary.

INDUSTRY TRENDS

  • M&A activity accelerated sharply in 2026, with deal volume nearly tripling YOY to $97.2 billion, reflecting growing confidence and continued platform-building across the sector.  
  • The IPO market rebounded after several muted years, reaching $6.8 billion in offerings as investor confidence in life sciences strengthens.  
  • AI-driven drug discovery continues to attract record investment, reshaping development timelines and drawing $7.8 billion in funding, up 49% YOY. 

  >> Access Industry Trends

GLOBAL OVERVIEW

  • Global lab and cGMP rents softened, declining 0.5% YOY as vacancy climbed to 24.2% amid newly delivered space, though the pace of increase is decelerating.  
  • Global R&D investment sales totaled $13.2 billion, up 2% YOY, with the Americas leading and EMEA posting the strongest regional growth.  
  • V.C. funding accelerated sharply, reaching $29.9 billion in the first half of 2026, up 30% YOY and the strongest first-half performance since 2022.  
  • Partnership activity surged to $108 billion, up 18% YOY, as pharma and biotech leaned more heavily on collaborations to advance pipelines. 

    >> Access Global Overview

U.S. OVERVIEW

  • Asking rents softened further but still sit well above office rents. Vacancy remains elevated at 24.3%, though the construction pipeline has tightened to just 2% of inventory, with nearly two-thirds of space under construction already preleased. 
  • R&D investment sales totaled $9.3 billion, up 4% YOY, while VC funding surged 37% and IPO volume climbed 232% YOY, outpacing full-year 2025 activity. 
  • Labor market conditions remain competitive for specialized roles even as job postings outpace hiring, with companies continuing to prioritize established hub markets for talent. 
  • Emerging U.S. markets continue to expand, supported by growing inventory, strong funding inflows, and expanding talent pipelines—offering cost-effective alternatives for both space and workforce needs. 

  >> Access U.S. Overview

CANADA OVERVIEW

  • Life sciences gross domestic product (GDP) growth outperformed the broader economy, supporting sustained demand for lab and manufacturing space. 
  • Life sciences employment growth has outpaced overall national employment growth over the past six years. 

  >> Access Canada Overview

EMEA OVERVIEW

  • Confidence is gradually returning, supported by improving debt markets, stronger VC flows, and renewed public sector funding, helping lift corporate activity and occupier sentiment. 
  • Vertical integration and growing AI adoption are helping optimize R&D strategies and lab design, positioning European markets for increasing momentum through 2026. 
  • Prime rents in the UK remain fragmented, with fitted space in Oxford now commanding rents above previous benchmarks and widening the gap between quoted and achieved rents across the Golden Triangle. 
  • New UK supply is rebalancing the market, with 825,000 square feet (sf) delivered across the Golden Triangle in H1 2026 as developments that started roughly two years ago reach completion. 

  >> Access Europe Overview

CHINESE MAINLAND OVERVIEW

  • Strong consumer spending and pro-consumption policies are supporting growing demand for healthcare products and services, creating fertile ground for biotech and medtech expansion. 
  • The Chinese mainland continues to advance up the global life sciences value chain, driven by sustained R&D investment and accelerated licensing activity, with out-licensing value reaching $99.7 billion in H1 2026, up 73% from full-year 2025. 
  • Biotech innovative drug launches overtook chemical drugs for the first time in H1 2026, reinforcing R&D momentum and elevating the region's influence in the global life sciences ecosystem. 

  >> Access Chinese Mainland Overview

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